Author

I. L. Bado

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 3 Research Focus:clustering· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

H. Wang· 4 shared J. Liu· 4 shared W. Zhang· 4 shared Z. Xu· 3 shared C. H. Rivas· 2 shared D. G. Edwards· 2 shared D. Hoffman· 2 shared E. Chen· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

H. Wang

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4 papers

Recent·Most cited

Single cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization.

F. Liu, Y. Ding, Z. Xu, X. Hao, T. Pan, G. Miles, C. H. Rivas, D. Hoffman, D. G. Edwards, E. Chen, H. Wang, H. L. Chan, J. Liu, L. Wu, L. Yu, , X. Zhang

The paper analyzes bone metastases from six cancer types using single-cell RNA-seq to identify three immune archetypes and their mechanisms of bone colonization.

bioRxiv · May 7, 2024Cancer Biology

Unbiased metastatic niche-labeling identifies estrogen receptor-positive macrophages as a barrier of T cell infiltration during bone colonization

Z. Xu, F. Liu, Y. Ding, T. Pan, Y.-H. Wu, J. Liu, I. L. Bado, W. Zhang, L. Wu, Y. Gao, X. Hao, L. Yu, D. G. Edwards, H. L. Chan, S. Aguirre, , X. H.- F. Zhang

bioRxiv · May 7, 2024 · PreprintCancer Biology

The bone microenvironment invigorates metastatic seeds for further dissemination

W. Zhang, I. L. Bado, H. Wang, S. Singh, H.-C. Lo, M. Niu, Z. Xu, J. Liu, W. Jiang, Y. Li, J. Hu, X. H. - F. Zhang

This study shows the bone microenvironment enhances metastatic potential of cancer cells, enabling further dissemination and multi-organ metastasis, independent of genetic selection.

bioRxiv · Nov 16, 2020Cancer Biology

Phenotypic plasticity of ER+ breast cancer in the bone microenvironment

I. L. Bado, H. Wang, P. Sarkar, J. Liu, W. Wu, W. Zhang, H.-C. Lo, A. Muscallera, M. Janghorban, I.-S. Kim, S. Singh, A. Goldstein, P. Singh, H. Shixia, G. M. Waleed, , X. H. F. Zhang

The paper shows that the bone microenvironment induces endocrine resistance in ER+ breast cancer metastases through epigenomic reprogramming mediated by EZH2.

bioRxiv · Nov 14, 2020 · PreprintCancer Biology