Author

I. O. Rosas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

A. C. Habermann· 2 shared A. J. Gutierrez· 2 shared D. Sales· 2 shared F. Romero· 2 shared J. A. Kropski· 2 shared J. C. Schupp· 2 shared K. Cuevas-Mora· 2 shared L. T. Bui· 2 shared

Activity by Year

2020-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

A. C. Habermann

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Author profile →

4 papers

Recent·Most cited

Integrated Single Cell Atlas of Endothelial Cells of the Human Lung

J. C. Schupp, T. S. Adams, C. Cosme, M. S. Brickman Raredon, N. Omote, S. Poli, K.-A. Rose, E. Manning, M. Sauler, G. DeIuliis, F. Ahangari, N. Neumark, Y. Yuan, A. C. Habermann, A. J. Gutierrez, , N. Kaminski

The paper reanalyzes six scRNA-seq datasets to create a comprehensive reference atlas of human lung endothelial cells, identifying new subpopulations and confirming their conservation in mice.

bioRxiv · Oct 21, 2020Cell Biology

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

L. T. Bui, N. I. Winters, M.-I. Chung, C. Joseph, A. J. Gutierrez, A. C. Habermann, T. S. Adams, J. C. Schupp, S. Poli, L. M. Peter, C. J. Taylor, J. B. Blackburn, B. W. Richmond, A. G. Nicholson, D. Rassl, , Human Cell Atlas Lung Biological Network

The paper analyzes single-cell transcriptomes from healthy and chronic lung disease lungs to identify gene expression programs linked to SARS-CoV-2 entry and severity.

bioRxiv · Oct 20, 2020Cell Biology

Transcriptomics, metabolomics and lipidomics of chronically injured alveolar epithelial cells reveals similar features of IPF lung epithelium

W. Roque, K. Cuevas-Mora, D. Sales, W. V. Li, I. O. Rosas, F. Romero

This study uses an in vitro model of chronic alveolar epithelial injury to reveal transcriptomic, metabolomic, and lipidomic features similar to those in IPF lung epithelium.

bioRxiv · May 8, 2020 · PreprintCell Biology

Impaired HSF1 transactivation drives proteostasis collapse and senescent phenotype of IPF lung fibroblast.

K. Cuevas-Mora, W. Roque, D. Sales, J. D. Ritzenthaler, E. Torres-Gonzales, A. J. Halayko, I. O. Rosas, J. Roman, F. Romero

This study shows that impaired HSF1 transactivation leads to proteostasis collapse and senescent phenotype in IPF lung fibroblasts, suggesting HSF1 activation could treat lung fibrosis.

bioRxiv · Apr 10, 2020 · PreprintCell Biology