Author

I. Sola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

L. Enjuanes· 4 shared C. Wang· 2 shared D. Drabek· 2 shared F. Grosveld· 2 shared R. Fernandez-Delgado· 2 shared R. van Haperen· 2 shared W. Li· 2 shared A. D. Osterhaus· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

L. Enjuanes

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants

W. Du, D. L. Hurdiss, D. Drabek, A. Z. Mykytyn, F. Kaiser, M. Gonzalez-Hernandez, D. Munoz-Santos, M. M. Lamers, R. van Haperen, W. Li, I. Drulyte, C. Wang, I. Sola, F. Armando, G. Beythien, , B. J. Bosch

bioRxiv · Feb 17, 2022 · PreprintMicrobiology

Isolation of cross-reactive monoclonal antibodies against divergent human coronaviruses that delineate a conserved and vulnerable site on the spike protein

C. Wang, R. van Haperen, J. Gutierrez-Alvarez, W. Li, N. Okba, I. Albulescu, I. Widjaja, B. van Dieren, R. Fernandez-Delgado, I. Sola, D. Hurdiss, O. Daramola, F. Grosveld, F. van Kuppeveld, B. Haagmans, , B.-J. Bosch

This study isolates two cross-reactive monoclonal antibodies against multiple Betacoronaviruses, identifying a conserved vulnerable site on the spike protein.

bioRxiv · Oct 20, 2020 · PreprintMicrobiology

Cross-neutralization activity against SARS-CoV-2 is present in currently available intravenous immunoglobulins

J. M. Diez, C. Romero, J. Vergara Alert, M. Bello Perez, J. Rodon, J. M. Honrubia, J. Segales, I. Sola, L. Enjuanes, R. Gajardo

This study shows that currently available IVIG products neutralize SARS-CoV-2 and SARS-CoV in cell cultures but not MERS-CoV.

bioRxiv · Jun 19, 2020Immunology

The deubiquitinating activity of Middle East respiratory syndrome coronavirus papain-like protease delays the innate immune response and enhances virulence in a mouse model

R. Knaap, R. Fernandez-Delgado, T. J. Dalebout, N. Oreshkova, P. J. Bredenbeek, L. Enjuanes, I. Sola, E. J. Snijder, M. Kikkert

This study shows that disrupting the deubiquitinating activity of MERS-CoV PLpro enhances innate immune responses and reduces virulence in mice.

bioRxiv · Aug 29, 2019 · PreprintMicrobiology