Author

C. M. Fernandes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:drug response / drug discovery· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. Del Poeta· 4 shared A. C. Colabardini· 1 shared A. K. Beach· 1 shared A. Selmecki· 1 shared C. Gautier· 1 shared C. Martins· 1 shared C. Maufrais· 1 shared C. Silva Pereira· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersMicrobiology

M. Del Poeta

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans.

P. V. Zande, C. Gautier, N. Kawar, C. Maufrais, K. Metzner, E. Wash, A. K. Beach, R. Bracken, E. I. Maciel, C. M. Fernandes, N. V. Solis, M. Del Poeta, S. G. Filler, J. Berman, I. V. Ene, A. Selmecki

This study shows how azole resistance in Candida albicans evolves through copy number variation followed by KSR1 loss of heterozygosity, resulting in a >500-fold resistance increase.

bioRxiv · Mar 5, 2024 · PreprintMicrobiology

Microdomain protein Nce102 is a local sensor of plasma membrane sphingolipid balance

J. Zahumensky, C. M. Fernandes, P. Vesela, M. Del Poeta, J. B. Konopka, J. Malinsky

The paper shows Nce102 senses sphingolipid balance at the plasma membrane by redistributing in response to sphingolipid demand and regulating sphingolipid synthesis.

bioRxiv · Dec 6, 2021Cell Biology

Screening of chemical libraries for new antifungal drugs against Aspergillus fumigatus reveals the potential mechanism of action of miltefosine

T. F. dos Reis, M. A. C. Horta, A. C. Colabardini, C. M. Fernandes, L. P. Silva, R. Bastos, M. V. L. Fonseca, F. Wang, C. Martins, M. Rodrigues, C. Silva Pereira, M. Del Poeta, K. H. Wong, G. H. Goldman

This study screens 1,127 compounds against Aspergillus fumigatus, identifies miltefosine as fungicidal, and reveals RmiA as a transcription factor regulating sphingolipid biosynthesis involved in miltefosine resistance.

bioRxiv · May 19, 2021Microbiology

Internalization of the host alkaline pH signal in a fungal pathogen

H. E. Brown, J. A. Alspaugh, K. M. Pianalto, K. D. Mueller, C. M. Fernandes, M. Del Poeta

This study identifies how the Rra1 protein in Cryptococcus neoformans internalizes and recycles in response to alkaline pH, enabling the fungus to adapt to the human host environment.

bioRxiv · Oct 19, 2020 · PreprintCell Biology