Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
P. X. Altman, M. Parren, H. Sang, G. Ozorowski, W.-H. Lee, V. V. Smider, I. A. Wilson, A. B. Ward, W. Mwangi, D. R. Burton, D. Sok
This study investigates whether engineering HIV Env trimers or using gp120 can induce broadly neutralizing antibodies in cows, finding that trimers are more effective than monomeric gp120.
bioRxiv · Mar 20, 2024 · PreprintImmunology
P. Altman, G. Ozorowski, R. Stanfield, J. Haakenson, M. Appel, M. Parren, W.-H. Lee, H. Sang, J. Woehl, K. Saye-Francisco, C. Joyce, G. Song, K. Porter, E. Landais, R. Andrabi, , D. Sok
This study immunized cows with HIV Env trimers to generate broadly neutralizing antibodies targeting the V2-apex, revealing ultralong CDRH3 antibodies outcompete shorter ones in the response.
bioRxiv · Feb 13, 2024Immunology
P. Zhou, G. Song, W.-t. He, N. Beutler, L. V. Tse, D. R. Martinez, A. Schafer, F. Anzanello, P. Yong, L. Peng, K. Dueker, R. Musharrafieh, S. Callaghan, T. Capozzola, M. Yuan, , R. Andrabi
The paper identifies broadly neutralizing antibodies targeting the S2 region of betacoronavirus spikes that protect against SARS-CoV-1, SARS-CoV-2, and MERS-CoV.
bioRxiv · Mar 4, 2022Immunology
W.-t. He, R. Musharrafieh, G. Song, K. Dueker, L. V. Tse, D. R. Martinez, A. Schafer, S. Callaghan, P. Yong, N. Beutler, J. L. Torres, R. M. Volk, P. Zhou, M. Yuan, H. Liu, , R. Andrabi
This study isolates a panel of broadly neutralizing antibodies against SARS-like viruses from donors, showing effectiveness against multiple variants including Omicron.
bioRxiv · Sep 8, 2021Immunology
W.-t. He, M. Yuan, S. Callaghan, R. Musharrafieh, G. Song, M. Silva, N. Beutler, W.-H. Lee, P. Yong, J. L. Torres, M. Melo, P. Zhou, F. Zhao, X. Zhu, L. Peng, , R. Andrabi
This study shows that rhesus macaques can be immunized to produce broadly neutralizing antibodies against multiple SARS-related viruses, highlighting differences in B cell repertoires between humans and macaques.
bioRxiv · Jul 5, 2021Immunology
M. A. Bakowski, N. Beutler, E. Chen, T.-T. H. Nguyen, M. G. Kirkpatrick, M. Parren, L. Yang, J. Ricketts, A. K. Gupta, M. V. Hull, P. G. Schultz, D. R. Burton, A. K. Chatterjee, C. W. McNamara, T. F. Rogers
The paper identifies 66 compounds that inhibit SARS-CoV-2 replication and 24 that synergize with remdesivir, suggesting potential oral drug repositioning candidates for COVID-19.
Nature Communications · Jun 3, 2021Peer-reviewedMicrobiology
P. Zhou, M. Yuan, G. Song, N. Beutler, N. Shaabani, D. Huang, W.-t. He, X. Zhu, S. Callaghan, P. Yong, F. Anzanello, L. Peng, J. Ricketts, M. Parren, E. Garcia, , R. Andrabi
This study identifies a broadly neutralizing antibody that targets a conserved site on beta-coronavirus spike proteins and provides protection against SARS-CoV-2 infection.
bioRxiv · Mar 30, 2021Immunology
G. Song, W.-t. He, S. Callaghan, F. Anzanello, D. Huang, J. Ricketts, J. L. Torres, N. Beutler, L. Peng, S. Vargas, J. Cassell, M. Parren, L. Yang, C. Ignacio, D. M. Smith, , R. Andrabi
The paper examines cross-reactive serum and memory B cell responses to SARS-CoV-2 and endemic coronaviruses, finding weak serum cross-reactivity but stronger memory B cell cross-reactivity.
bioRxiv · Sep 22, 2020Immunology
T. F. Rogers, F. Zhao, D. Huang, N. Beutler, A. Burns, W.-t. He, O. Limbo, C. Smith, G. Song, J. Woehl, L. Yang, R. K. Abbott, S. Callaghan, E. Garcia, J. Hurtado, , D. Burton
This study rapidly identifies potent SARS-CoV-2 neutralizing antibodies and demonstrates their protective efficacy in an animal model.
bioRxiv · May 11, 2020Immunology