I.-J. Cho

Target Class Profiling of Small Molecule Methyltransferases

The paper develops a target class profiling approach to study small molecule methyltransferases, identifies a novel HNMT inhibitor, and demonstrates its utility for drug discovery.

Human spinal cord organoids exhibiting neural tube morphogenesis for a quantifiable drug screening system of neural tube defects

This study develops human spinal cord-like organoids (hSCOs) to enable quantitative drug screening for neural tube defects.