Author

Isabella Biscocho

Altos Labs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Adam R. RensloiD· 1 shared Adam S. FrostiD· 1 shared Aniliese DealiD· 1 shared Christopher P. ArthuriD· 1 shared D. John LeeiD· 1 shared Hongyi Zhou· 1 shared Junhua Wang· 1 shared Kimberly PrescottiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Adam R. RensloORCID

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Author profile →

1 paper

Recent·Most cited

Stereoselective methyl-swapping demonstrates target specificity of cognitive enhancer

Morgane Boone, Udit Dalwadi, Aniliese Deal, Ping Zhu, Tristan Ian Croll, Maya Yamazaki, Kimberly Prescott, Renato Minopoli, Isabella Biscocho, Junhua Wang, D. John Lee, Christopher P. Arthur, Thomas G. Laughlin, Hongyi Zhou, Matthew T. Klope, , Peter Walter

The paper demonstrates that a modified ISRIB analog selectively targets a mutant eIF2B, improving synaptic plasticity and memory in mice, confirming its on-target mechanism.

bioRxiv · Feb 7, 2026 · PreprintBiochemistry