Author

J. A. Herrera

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Biochemistry· 1 Biophysics· 1 Cell Biology· 1 Immunology· 1

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Research Focus:cell type annotation· 5 Assay:proteomics· 5 Approach:experimental assay· 4 Organism:human· 4 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2

Frequent Co-Authors

C. Lawless· 4 shared M. A. Montero· 3 shared J. Chang· 2 shared K. E. Kadler· 2 shared L. Dingle· 2 shared M. A. Schwartz· 2 shared R. V. Venkateswaran· 2 shared S. Rosini· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersPathology

C. Lawless

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Modelling collagen fibril self-assembly from extracellular medium in embryonic tendon

C. K. Revell, J. A. Herrera, C. Lawless, Y. Lu, K. E. Kadler, J. Chang, O. E. Jensen

The paper models collagen fibril self-assembly in embryonic mouse tendon, showing that fibrils form extracellularly through a phase-transition mechanism, supported by experimental data.

bioRxiv · Mar 13, 2023Biophysics

The UIP honeycomb airway cells are the site of mucin biogenesis with deranged cilia

J. A. Herrera, L. A. Dingle, M. A. Montero, V. Rajamiyer, J. Blaikley, F. Granato, S. Pearson, C. Lawless, D. J. Thornton

The paper uses spatial proteomics to compare fibrotic and non-fibrotic airway cells in UIP, finding deregulated pathways and identifying key proteins associated with mucin biogenesis and ciliogenesis.

bioRxiv · Sep 3, 2022Pathology

The IPF fibroblastic focus is an active collagen biosynthesis factory embedded in a distinct extracellular matrix

J. A. Herrera, L. Dingle, M. A. Montero, R. Shah, R. V. Venkateswaran, J. F. Blaikley, C. Lawless, M. A. Schwartz

The paper uses spatial proteomics to show that the IPF fibroblastic focus is a major site of collagen biosynthesis with distinct ECM composition compared to surrounding tissues.

bioRxiv · Nov 6, 2021Pathology

Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

J. CHANG, A. PICKARD, J. A. Herrera, S. O'Keefe, M. Hartshorn, R. GARVA, A. Hoyle, L. Dingle, C. Zeltz, J. Wong, A. Reid, R. V. Venkateswaran, Y. Lu, P. Caswell, S. High, , K. E. KADLER

This study shows that circadian-regulated endocytic recycling is essential for collagen fibril assembly and is disrupted in fibrosis.

bioRxiv · Mar 25, 2021Cell Biology

IL-13 deficiency exacerbates lung damage and impairs epithelial-derived type 2 molecules during nematode infection

A. L. Chenery, S. Rosini, J. Parkinson, J. A. Herrera, C. Lawless, B. H. Chan, P. A. Loke, A. S. MacDonald, K. Kadler, T. E. Sutherland, J. E. Allen

This study shows that IL-13 reduces lung damage and supports epithelial type 2 molecule production during nematode infection in mice.

bioRxiv · Oct 14, 2020Immunology

Laser capture microdissection coupled mass spectrometry (LCM-MS) for spatially resolved analysis of formalin-fixed and stained human lung tissues

J. A. Herrera, V. Mallikarjun, S. Rosini, M. A. Montero, S. Warwood, R. O'Caulian, D. Knight, M. A. Schwartz, J. Swift

This paper develops an optimized microproteomics method for analyzing H&E-stained FFPE lung tissues, identifying 1252 differentially expressed proteins including 137 ECM proteins.

bioRxiv · Aug 13, 2019Biochemistry