Author

J. A. MacGurn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 6

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Research Focus:cell signaling & trafficking· 6 Approach:experimental assay· 6 Assay:proteomics· 6 Organism:yeast· 4 Research Focus:chromatin & epigenetic regulation· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

N. L. Hepowit· 3 shared L. P. Jackson· 2 shared N. S. Diab· 2 shared P. Xu· 2 shared T. R. Graham· 2 shared B. J. Moon· 1 shared B. Xie· 1 shared C. Macdonald· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

N. L. Hepowit

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6 papers

Recent·Most cited

Art2 mediates selective endocytosis of methionine transporters during adaptation to sphingolipid depletion

N. L. Hepowit, B. J. Moon, R. C. Dickson, J. A. MacGurn

The paper shows that sphingolipid depletion causes selective endocytosis of methionine transporters via Art2-mediated ubiquitination, altering nutrient transporter composition at the cell surface.

bioRxiv · May 20, 2022Cell Biology

Ubiquitination drives COPI priming and Golgi SNARE localization

S. S. Date, P. Xu, N. L. Hepowit, N. S. Diab, J. Best, B. Xie, J. Du, E. R. Strieter, L. P. Jackson, J. A. MacGurn, T. R. Graham

The paper identifies ubiquitin recognition by COPI as essential for Golgi SNARE localization and stabilizing interactions between Arf, COPI, and SNAREs.

bioRxiv · Nov 29, 2021Cell Biology

Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast

N. L. Hepowit, K. N. Pereira, J. M. Tumolo, W. J. Chazin, J. A. MacGurn

This study identifies Ser57 ubiquitin kinases in yeast and human cells that regulate the oxidative stress response by phosphorylating ubiquitin at Ser57.

bioRxiv · Jun 20, 2020Cell Biology

USP9X deubiquitylates DVL2 to regulate WNT pathway specification

C. P. Nielsen, K. K. Jernigan, N. Diggins, D. Webb, J. A. MacGurn

The paper identifies USP9X and WWP1 as regulators of DVL2 ubiquitylation, which determines its involvement in canonical or non-canonical WNT pathways.

bioRxiv · Jun 1, 2019Cell Biology

The yeast Art1 arrestin domain contains disordered insertions that regulate its localization and activity

M. G. Baile, E. L. Guiney, E. J. Sanford, J. A. MacGurn, M. B. Smolka, S. D. Emr

The paper identifies loop insertions in the yeast Art1 protein that regulate its localization and activity through phosphorylation and cargo specificity.

bioRxiv · Feb 18, 2019Cell Biology

COPI Mediates Recycling Of An Exocytic SNARE From Endosomes By Recognition Of A Ubiquitin Sorting Signal

P. Xu, H. Hankins, C. Macdonald, S. J. Erlinger, M. Frazier, N. S. Diab, R. C. Piper, L. P. Jackson, J. A. MacGurn, T. R. Graham

This study shows COPI mediates recycling of the SNARE Snc1 from early endosomes to the Golgi via recognition of a polyubiquitin sorting signal.

bioRxiv · May 3, 2017Cell Biology