Author

R. C. Piper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 5 Approach:experimental assay· 5 Assay:proteomics· 4 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

A. Y. Minard· 2 shared B. A. Davies· 2 shared J. A. Payne· 2 shared N. Pashkova· 2 shared A. d. Bruin· 1 shared B. G. Childs· 1 shared C. A. Ahern· 1 shared C. Allamargot· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiophysics

A. Y. Minard

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Beta-subunit-eliminated eHAP expression (BeHAPe) cells reveal new properties of the cardiac voltage-gated sodium channel

A. Y. Minard, C. J. Clark, C. A. Ahern, R. C. Piper

The paper develops a cell line lacking endogenous NaV β-subunits to better study their effects on NaV1.5, revealing unique gating properties and hybrid behavior when multiple β-subunits are combined.

bioRxiv · Jul 8, 2023 · PreprintBiophysics

Dynein-mediated trafficking and degradation of nephrin in diabetic podocytopathy

H. Sun, J. Weidner, C. Allamargot, R. C. Piper, J. Misurac, C. Nester

This study identifies dynein-mediated trafficking and degradation of nephrin as a key mechanism in diabetic podocytopathy, showing increased dynein expression and its role in nephrin mistrafficking.

bioRxiv · Oct 1, 2022 · PreprintPhysiology

HD-PTP/PTPN23 hypomorphic mice display lipodystrophy

B. A. Davies, J. A. Payne, C. P. Martin, D. Schultz, B. G. Childs, C. Zhang, K. Jeganathan, I. Sturmlechner, T. A. White, A. d. Bruin, H. Chen, M. A. Davies, S. Jachim, N. K. LeBrasseur, R. C. Piper, , D. J. Katzmann

This study shows that hypomorphic HD-PTP/PTPN23 mice develop lipodystrophy and reduced adipogenesis, indicating HD-PTP's role in insulin signaling and fat accumulation.

bioRxiv · Aug 2, 2022 · PreprintCell Biology

ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals.

N. Pashkova, L. Gakhar, S. Winistorfer, A. Y. Minard, N. J. Schnicker, L. Yu, I. E. Johnson, R. C. Piper

The paper identifies ANTH domains in CALM, HIP1R, and Sla2 that bind ubiquitin, contributing to clathrin-mediated endocytosis of ubiquitinated membrane proteins.

eLife · Nov 25, 2021Peer-reviewedCell Biology

Bro1 stimulates Vps4 activity to promote Intralumenal Vesicle Formation during Multivesicular Body biogenesis

C.-c. Tseng, S. Dean, B. A. Davies, I. F. Azmi, N. Pashkova, J. A. Payne, J. Staffenhagen, M. West, R. C. Piper, G. Odorizzi, D. Katzmann

This study shows that the Bro1 V domain stimulates Vps4 activity to promote ESCRT-III-driven intralumenal vesicle formation during MVB biogenesis, coordinating cargo sorting with membrane remodeling.

bioRxiv · Jul 27, 2020Cell Biology

COPI Mediates Recycling Of An Exocytic SNARE From Endosomes By Recognition Of A Ubiquitin Sorting Signal

P. Xu, H. Hankins, C. Macdonald, S. J. Erlinger, M. Frazier, N. S. Diab, R. C. Piper, L. P. Jackson, J. A. MacGurn, T. R. Graham

This study shows COPI mediates recycling of the SNARE Snc1 from early endosomes to the Golgi via recognition of a polyubiquitin sorting signal.

bioRxiv · May 3, 2017Cell Biology