Author

J. A. Todd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2

Frequent Co-Authors

A. J. Cutler· 3 shared L. S. Wicker· 3 shared M. L. Pekalski· 3 shared R. C. Ferreira· 3 shared A. Rubio Garcia· 2 shared C. Wallace· 2 shared D. B. Dunger· 2 shared D. B. Rainbow· 2 shared

Activity by Year

2016-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersImmunology

A. J. Cutler

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Peripheral tolerance to insulin is encoded by mimicry in the microbiome

A. Rubio Garcia, A. Paterou, M. Lee, H. Slawinski, L. S. Wicker, J. A. Todd, M. L. Pekalski

The paper identifies microbial mimicry of insulin epitopes in the gut microbiome as a potential cause of type 1 diabetes by showing that transketolase mimotopes trigger immune responses similar to insulin.

bioRxiv · Dec 18, 2019 · PreprintImmunology

Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

D. Trzupek, M. Dunstan, A. J. Cutler, M. Lee, L. Godfrey, D. Aschenbrenner, H. H. Uhlig, L. Wicker, J. A. Todd, R. C. Ferreira

The paper uses a hybrid transcriptomic and proteomic approach to identify CD80 and CD86 as markers of recently activated regulatory T cells in human CD4+ T cells.

bioRxiv · Nov 29, 2019Immunology

The origin and diversification of pteropods predate past perturbations in the Earth’s carbon cycle

K. T. C. A. Peijnenburg, A. W. Janssen, D. Wall-Palmer, E. Goetze, A. Maas, J. A. Todd, F. Marletaz

This study reconstructs the evolutionary history of pteropods using phylogenomic data and fossils, showing their resilience to past carbon cycle perturbations.

bioRxiv · Oct 21, 2019Evolutionary Biology

Cells With Treg-Specific FOXP3 Demethylation But Low CD25 Are Prevalent In Autoimmunity

R. C. Ferreira, H. Z. Simons, W. Thompson, D. B. Rainbow, X. Yang, A. J. Cutler, J. Oliveira, X. C. Dopico, D. J. Smyth, N. Savinykh, M. Mashar, T. Vyse, D. B. Dunger, H. Baxendale, A. Chandra, , M. L. Pekalski

The paper identifies CD25lowFOXP3+ T cells as a subset of regulatory T cells expanded in autoimmune diseases, characterized by FOXP3 demethylation and distinct functional features.

bioRxiv · May 5, 2017Immunology

Recent thymic emigrants produce antimicrobial IL-8, express complement receptors and are precursors of a tissue-homing Th8 lineage of memory cells

M. L. Pekalski, A. Rubio Garcia, R. C. Ferreira, D. B. Rainbow, D. J. Smyth, M. Mashar, J. Brady, N. Savinykh, X. Castro Dopico, S. Mahmood, S. Duley, H. E. Stevens, N. M. Walker, A. J. Cutler, F. Waldron-Lynch, , L. S. Wicker

The paper identifies CR2+ naive T cells as recent thymic emigrants that express antimicrobial IL-8 and complement receptors, and may become tissue-homing memory cells.

bioRxiv · Jun 17, 2016Immunology