Process Development and Scale-up Optimization of the SARS-CoV-2 Receptor Binding Domain-Based Vaccine Candidate, RBD219-N1C1
J. Lee, Z. Liu, W.-H. Chen, J. Wei, R. Kundu, R. Adhikari, J. Altieri Rivera, P. M. Gillespie, U. Strych, B. Zhan, P. J. Hotez, M. E. Bottazzi
The paper optimizes the production process for a SARS-CoV-2 vaccine candidate, achieving high yield and purity through yeast fermentation and chromatographic purification.
bioRxiv · Dec 30, 2020Immunology