High-affinity, neutralizing antibodies to SARS-CoV-2 can be made in the absence of T follicular helper cells
J. S. Chen, R. D. Chow, E. Song, T. Mao, B. Israelow, K. Kamath, J. Bozekowski, W. A. Haynes, R. B. Filler, B. L. Menasche, J. Wei, M. M. Alfajaro, W. Song, L. Peng, L. Carter, , S. C. Eisenbarth
The paper shows that high-affinity, neutralizing antibodies against SARS-CoV-2 can be produced without T follicular helper cells through alternative pathways.
bioRxiv · Jun 10, 2021Immunology