Author

J. C. Edwards

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Organism:mouse· 1 Organism:plant (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Burman· 1 shared A. C. Hendry· 1 shared A. J. Spencer· 1 shared A. Ludi· 1 shared A. S. Asfor· 1 shared B. Charleston· 1 shared C. Browning· 1 shared C. Chiu· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

A. Burman

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2 papers

Recent·Most cited

Zn2+ triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels

L. Varela, A. C. Hendry, J. Cassar, R. Martin-Escolano, D. Cantoni, J. C. Edwards, V. B. Abdul-Salam, J. L. Ortega-Roldan

This study identifies Zn2+ binding as the molecular switch for CLIC1 membrane insertion and pH-dependent chloride efflux activation.

bioRxiv · Oct 25, 2021Biochemistry

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

S. P. Graham, R. K. McLean, A. J. Spencer, S. Belij-Rammerstorfer, D. Wright, M. Ulaszewska, J. C. Edwards, J. W. P. Hayes, V. Martini, N. Thakur, C. Conceicao, I. Dietrich, H. Shelton, R. Waters, A. Ludi, , T. Lambe

This study evaluates the immunogenicity of single and booster doses of the ChAdOx1 nCoV-19 vaccine in mice and pigs, finding that a booster significantly enhances antibody responses, especially in pigs.

bioRxiv · Jun 20, 2020Immunology