Author

J. C. Garcia-Garcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Brown· 2 shared B. Willard· 2 shared C. Neumann· 2 shared J. M. Brown· 2 shared J. T. Anderson· 2 shared K. K. Fung· 2 shared R. C. Schugar· 2 shared R. N. Helsley· 2 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

A. L. Brown

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Gut Microbial Trimethylamine is Elevated in Alcohol-Associated Hepatitis and Contributes to Ethanol-Induced Liver Injury in Mice

R. N. Helsley, T. Miyata, A. Kadam, V. Venkateshwari, N. Sangwan, E. C. Huang, R. Banerjee, A. L. Brown, K. K. Fung, W. Massey, C. Neumann, O. Danny, L. J. Osborn, R. C. Schugar, M. R. McMullen, , J. M. Brown

This study shows elevated trimethylamine (TMA) in alcohol-associated hepatitis patients and demonstrates that inhibiting gut microbial TMA production protects mice from ethanol-induced liver injury.

bioRxiv · Dec 31, 2021Biochemistry

Gut Microbe-Targeted Choline Trimethylamine Lyase Inhibition Improves Obesity Via Rewiring of Host Circadian Rhythms

R. C. Schugar, C. M. Gliniak, R. N. Helsley, A. L. Brown, A. Burrows, C. Finney, K. K. Fung, F. M. Allen, D. Ferguson, A. D. Gromovsky, C. Neumann, A. McMillan, J. A. Buffa, J. T. Anderson, M. Mehrabian, , J. M. Brown

The paper shows that inhibiting gut microbial choline TMA-lyase reduces obesity in mice by altering microbiome composition and host circadian rhythms.

bioRxiv · Dec 4, 2020Physiology