The Burkholderia cenocepacia type VI secretion system effector TecA is a virulence factor during lung infection
N. A. Loeven, A. I. Perault, P. A. Cotter, C. A. Hodges, J. D. Schwartzman, T. H. Hampton, J. B. Bliska
This paper demonstrates that TecA, a type VI secretion system effector of Burkholderia cenocepacia, acts as a virulence factor by exacerbating lung inflammation, weight loss, and lethality in a CF mouse model.
bioRxiv · Jul 13, 2021Microbiology