J. Dai

This study uses single-cell RNA sequencing to analyze transcriptomic heterogeneity in lymphoblastoid cell lines and shows how stochastic factors influence clonal evolution.

This study shows that Asgard archaea possess ESCRT complexes with eukaryotic-like structural and functional features, suggesting they are evolutionary precursors to eukaryotic ESCRTs.

This paper develops a SARS-CoV-2 proteome microarray to analyze antibody interactions at amino acid resolution and identifies epitopes and neutralizing antibodies in COVID-19 patients.

This study identifies AfRip3 as a key modulator of necroptotic death in A. fumigatus, showing it is induced by Ca2+ and activates JNK and SMase pathways.

The paper uses single-cell RNA sequencing to analyze immune cell composition in brain metastases of NSCLC patients, finding reduced T cell activity and expanded M2-polarized tumor-associated macrophages.

This study shows TRAP1 forms an OXPHOS-regulated tetramer and is essential for maintaining mitochondrial metabolic homeostasis by modulating OXPHOS and interacting with mitochondrial chaperones.

This study identifies mRNA biomarkers distinguishing EBV latency IIb and III states using transcriptomic analysis of EBV-infected B cells.

The paper examines geographic patterns of bacterioplankton in interconnected lakes of the Yangtze River Basin, finding that distance-decay relationships and stochastic processes dominate bacterial community assembly.

The paper uses intracellular BH3 profiling to analyze B-cell subsets and their anti-apoptotic dependencies during maturation and activation, revealing distinct dependencies in different stages.