Author

J. Dominguez-Andres

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

G. Kilic· 2 shared O. Bulut· 2 shared A. V. Ferreira· 1 shared A. Ziogas· 1 shared C. de Bree· 1 shared C. Khantwal· 1 shared D. S. Kantner· 1 shared E. A. Noel· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

G. Kilic

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Author profile →

3 papers

Recent·Most cited

Fatty acid desaturation and lipoxygenase pathways support trained immunity

A. V. Ferreira, J. C. Alarcon-Barrera, J. Dominguez-Andres, O. Bulut, G. Kilic, P. A. Debisarun, R. J. Röring, H. N. Özhan, E. Terschlüsen, A. Ziogas, S. Kostidis, Y. Mohammed, V. Matzaraki, G. Renieris, E. J. Giamarellos-Bourboulis, , M. Giera

This study identifies fatty acid desaturation and lipoxygenase pathways as essential for BCG-induced trained immunity in human monocytes.

Nature Communications · Nov 15, 2023Peer-reviewedImmunology

Coenzyme A governs proinflammatory macrophage metabolism

G. A. Timblin, K. M. Tharp, J. t. Hoeve, D. S. Kantner, I. Baydemir, E. A. Noel, C. Khantwal, P. K. Singh, J. N. Farahzad, J. Dominguez-Andres, R. E. Vance, N. W. Snyder, V. M. Weaver

This study shows that exogenous CoA enhances TLR-driven proinflammatory and antimicrobial responses in macrophages by promoting oxidative metabolism and histone acetylation.

bioRxiv · Aug 30, 2022 · PreprintImmunology

The Immunological Factors Predisposing To Severe COVID-19 Are Already Present In Healthy Elderly And Men

G. Kilic, O. Bulut, M. Jaeger, R. ter Horst, V. Koeken, S. J. C. F. M. Moorlag, V. Mourits, C. de Bree, J. Dominguez-Andres, L. A. B. Joosten, M. Netea

The paper identifies immunological factors associated with severe COVID-19 in healthy elderly and men, showing intrinsic differences in immune cell subsets and inflammatory proteins.

bioRxiv · Apr 30, 2021Immunology