Author

J. E. Bruin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

G. Matteo· 3 shared M. P. Hoyeck· 3 shared H. Blair· 2 shared K. R. Rick· 2 shared S. O'Dwyer· 2 shared A. C. Cheung· 1 shared A. M. Crawley· 1 shared A. M. E. Ching· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersPharmacology & Toxicology

G. Matteo

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

CD8 T cell hyperfunction and reduced tumour control in models of advanced liver fibrosis

J. Madani, J. Li, A. Vranjkovic, K. Jorritsma, M. S. Hasim, M. Daneshmand, A. C. Cheung, A. M. E. Ching, J. E. Bruin, M. Ardolino, A. M. Crawley

This study shows that chronic liver fibrosis leads to systemic CD8+ T cell hyperfunction, impairing tumor control and immune response.

bioRxiv · Sep 20, 2023 · PreprintImmunology

Prolonged low-dose dioxin exposure impairs metabolic adaptability to high-fat diet feeding in female but not male mice

G. Matteo, M. P. Hoyeck, H. L. Blair, J. Zebarth, K. R. Rick, A. Williams, R. Gagne, J. K. Buick, C. Yauk, J. E. Bruin

bioRxiv · Sep 12, 2020 · PreprintPharmacology & Toxicology

Female mice exposed to low-doses of dioxin during pregnancy and lactation have increased susceptibility to diet-induced obesity and diabetes

M. P. Hoyeck, R. C. Merhi, H. Blair, C. D. Spencer, M. A. Payant, D. I. Martin Alfonso, M. Zhang, G. Matteo, M. J. Chee, J. E. Bruin

This study shows that low-dose dioxin exposure during pregnancy and lactation in mice increases susceptibility to diet-induced obesity and diabetes later in life.

bioRxiv · Jul 9, 2020Pharmacology & Toxicology

Pancreas-specific miR-216a regulates proliferation and endocrine and exocrine cell function in vivo

S. Erener, C. E. Ellis, A. Ramzy, M. M. Glavas, S. O'Dwyer, S. Pereira, T. Wang, J. Pang, J. E. Bruin, M. J. Riedel, R. J. Baker, T. D. Webber, J. L. Kopp, S. Herzig, T. J. Kieffer

This study identifies miR-216a as a pancreas-specific miRNA that regulates cell proliferation and function in both endocrine and exocrine cells, with implications for diabetes and pancreatic cancer.

bioRxiv · Oct 7, 2019 · PreprintPhysiology

Long-term metabolic consequences of acute dioxin exposure differ between male and female mice

M. P. Hoyeck, H. Blair, M. Ibrahim, S. Solanki, M. Elsawy, A. Prakash, K. R. Rick, G. Matteo, S. O'Dwyer, J. E. Bruin

This study examines the long-term metabolic effects of acute dioxin exposure in male and female mice, revealing sex-dependent differences in insulin levels and beta cell function.

bioRxiv · Sep 9, 2019Pharmacology & Toxicology