Author

R. J. Baker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 2 Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Lautens· 2 shared A. R. Burns· 1 shared A. Ramzy· 1 shared A. Scheremetjew· 1 shared B. C. Faircloth· 1 shared B. Mirabi· 1 shared C. Dank· 1 shared C. E. Ellis· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

M. Lautens

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6

R. J. Harding, I. Franzoni, M. K. Mann, M. Szewczyk, B. Mirabi, D. D. Owens, S. Ackloo, A. Scheremetjew, K. A. Juarez-Ornelas, R. Sanichar, R. J. Baker, C. Dank, P. J. Brown, D. Barsyte-Lovejoy, V. Santhakumar, , C. H. Arrowsmith

The paper identifies and characterizes a chemical probe, SGC-UBD253, that targets the HDAC6 UBD with selectivity, and a less active derivative as a negative control.

bioRxiv · Feb 21, 2023Pharmacology & Toxicology

Nemacol is a Small Molecule Inhibitor of C. elegans Vesicular Acetylcholine Transporter with Anthelmintic Potential

S. Harrington, J. Pyche, A. R. Burns, T. Spalholz, R. J. Baker, J. Ching, M. Lautens, D. Kulke, W. Deuther-Conrad, P. Brust, P. J. Roy

A small molecule screen identifies a vesicular acetylcholine transporter inhibitor scaffold that incapacitates parasitic nematodes.

bioRxiv · Jun 14, 2022 · PreprintPharmacology & Toxicology

Pancreas-specific miR-216a regulates proliferation and endocrine and exocrine cell function in vivo

S. Erener, C. E. Ellis, A. Ramzy, M. M. Glavas, S. O'Dwyer, S. Pereira, T. Wang, J. Pang, J. E. Bruin, M. J. Riedel, R. J. Baker, T. D. Webber, J. L. Kopp, S. Herzig, T. J. Kieffer

This study identifies miR-216a as a pancreas-specific miRNA that regulates cell proliferation and function in both endocrine and exocrine cells, with implications for diabetes and pancreatic cancer.

bioRxiv · Oct 7, 2019 · PreprintPhysiology

Conflicting evolutionary histories of the mitochondrial and nuclear genomes in New World Myotis

R. N. Platt, B. C. Faircloth, K. A. M. Sullivan, T. Kieran, T. C. Glenn, M. W. Vandewege, T. E. Lee, R. J. Baker, R. D. Stevens, D. A. Ray

The study examines conflicting evolutionary histories between mitochondrial and nuclear genomes in New World Myotis using UCE data and mitochondrial genomes.

bioRxiv · Jun 16, 2017Evolutionary Biology