Author

C. Carrion

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 1 Microbiology· 1 Pathology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:mouse· 6 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

M. Cogne· 4 shared S. Bender· 4 shared S. Le Noir· 3 shared A. Bonaud· 2 shared C. Oblet· 2 shared C. Sirac· 2 shared E. Pinaud· 2 shared M. Brousse· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersImmunology

M. Cogne

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

REL deregulation stands as a primary hit for AID-imprinted B-cells along the germinal center competition

L. Prevaud, C. Vincent-Fabert, T. Marchiol, Q. Lemasson, C. Ouk, C. Carrion, M. Cogne, J. Feuillard, N. Faumont

This study shows REL deregulation gives AID-imprinted B-cells a competitive advantage in germinal centers, promoting expansion and potential transformation into aggressive lymphomas.

bioRxiv · Oct 10, 2023 · PreprintCancer Biology

Hospital and urban wastewaters shape the structure and active resistome of environmental biofilms

E. Buelow, C. Dauga, C. Carrion, H. Mathe-Hubert, S. Achaibou, M. Gaschet, T. Jove, O. Chesneau, S. P. Kennedy, M.-C. Ploy, S. Da Re, C. DAGOT

This study shows hospital and urban wastewater biofilms have distinct resistome structures and active antibiotic resistance gene expression, with hospital biofilms being a key hotspot for AMR dissemination.

bioRxiv · Jan 19, 2023Microbiology

A dual function for the chromatin organizer Special A-T rich Binding Protein 1 in B-lineage cells

M. Thomas, O. Martin, C. Bruzeau, J. Pollet, S. Bender, C. Carrion, S. Le Noir, E. Pinaud

This study investigates SATB1's role in B-lineage cells, finding it is not essential for B cell development but acts as both a positive and negative regulator of Ig gene transcription in naive and activated B cells, respectively.

bioRxiv · Sep 6, 2022 · PreprintImmunology

The IgH Eμ-MAR regions promote UNG-dependent error-prone repair to optimize somatic hypermutation

O. Martin, M. Thomas, M. Marquet, A. Garot, M. Brousse, S. Bender, C. Carrion, J. E. Choi, B. Vuong, P. Gearhart, R. Maul, S. Le Noir, E. Pinaud

The paper shows that IgH Eμ-MAR regions limit error-prone repair to the variable region of Ig genes by promoting UNG-dependent repair, affecting somatic hypermutation patterns.

bioRxiv · Aug 15, 2022 · PreprintImmunology

Diverse B-cell specific transcriptional contexts of the BCL2 oncogene in mouse models impacts pre-malignant development

L. Zawil, T. Marchiol, B. Brauge, A. Saint-Amand, C. Carrion, E. Dessauge, C. Oblet, S. Le Noir, F. Mourcin, F. Jouan, P. Derouault, M. Alizadeh, M. Brousse, Y. El Makhour, C. Monvoisin, , M. Cogne

The paper investigates how BCL2 oncogene deregulation in mouse models affects B-cell fate and pre-malignant development through two genetic constructs.

bioRxiv · Oct 28, 2021 · PreprintImmunology

New models to study plasma cells in mouse based on the restriction of IgJ expression to antibody secreting cells.

M. V. Ayala, A. Bonaud, S. Bender, J.-M. Lambert, F. Lechouane, C. Carrion, M. Cogne, V. Pascal, C. Sirac

The paper introduces two new mouse models, IgJGFP and IgJCreERT2, for studying plasma cells by leveraging IgJ expression as a marker for antibody-secreting cells.

bioRxiv · Aug 13, 2020 · PreprintImmunology

Assessing the social impact of an online course on the clinical management of Cutaneous Leishmaniasis: A qualitative study

C. Carrion, M. Aymerich, L. Arroyo, J. A. Ruiz-Postigo

This paper assesses the social impact of an online course on CL management through qualitative analysis of student experiences and outcomes.

bioRxiv · May 8, 2019 · PreprintScientific Communication & Education

Glomerulosclerosis and kidney failure in a mouse model of monoclonal immunoglobulin light-chain deposition disease

S. Bender, M. V. Ayala, A. Bonaud, V. Javaugue, C. Carrion, C. Oblet, A. Rinsant, N. Quellard, S. Kaaki, Z. Oruc, F. Boyer, A. Paquet, N. Pons, B. Herve, M. O. Ashi, , C. Sirac

This study develops a mouse model of light chain deposition disease, showing that pathogenic light chains cause glomerulosclerosis and kidney failure, and identifies potential therapeutic targets.

bioRxiv · May 2, 2019 · PreprintPathology