J. Feng

This paper characterizes two pectate lyases from Caldicellulosiruptor bescii, showing distinct degradation properties and roles of their CALG domain in plant biomass breakdown.

This paper introduces a BLSTM network to separate overlapping bat calls, achieving high separation quality and species classification accuracy.

This study applies r- and K-selection to HeLa cells to show how life history strategies influence tumor functional diversity through gene expression and ecological competition.

This study investigates how temperature and light affect the survival of Plasmodiophora brassicae resting spores in soil, finding that lower temperatures and burial improve survival while UV light reduces viability.

The paper uses gold nanorods to track fluid dynamics above swarming bacteria, revealing superdiffusive transport flows that enable long-range material transport and population-level communication.

This study demonstrates that combining antibiotics targeting both growing bacteria and persisters eradicates S. aureus biofilm infections more effectively than current treatments.

This study evaluates the antimicrobial activity of 12 botanical medicines and 3 natural agents against growing and non-growing forms of B. burgdorferi in vitro, identifying some with strong activity against non-growing cells.

This study identifies iRhom2 as a key regulator that promotes obesity-associated metabolic disorder by enhancing adipose inflammation and insulin resistance.

This study investigates the printability of metal ion crosslinked PEG-catechol inks, showing that ink composition and printing parameters affect shape fidelity and viability of cells seeded on the materials.

This study identifies genes regulating cell death in Staphylococcus aureus through a genome-wide screen, revealing both death-resistant and death-sensitive mutants with implications for virulence and antibiotic persistence.

This study shows that pre-infection modulation of host glycolysis with 2-DG enhances resistance to M. marinum infection by reducing phagocytosis and bacterial proliferation.

This study shows two Chloroflexi classes can persist using atmospheric hydrogen and carbon monoxide as energy sources through horizontal gene transfer.

This study characterizes the structure, function, and dynamics of the gamete fusogen HAP2, revealing dynamic regions and structural features critical for fusion.

This study presents a mechanical model of cell migration that reproduces durotaxis and contact guidance by simulating cell-substrate interactions through focal adhesions.

This study shows metformin improves uterine progesterone signaling in PCOS-like rats by reducing PGR and ER expression and correcting gene expression abnormalities.

This paper identifies 10 essential oils and cinnamaldehyde with high activity against stationary phase Borrelia burgdorferi, including complete eradication at 0.1% concentration.

This paper evaluates the activity of 34 essential oils against Borrelia burgdorferi stationary phase cells, identifying oregano, cinnamon bark, and clove bud as highly effective against persisters and biofilms, with carvacrol as the most active component.

The paper investigates how common tuberculosis drugs affect clofazimine activity in vitro and explores its potential for treating multi-drug-resistant TB.

This study identifies drugs that enhance pyrazinamide's anti-persister activity by screening a clinical drug library against M. tuberculosis cultures enriched with persisters.

This study evaluates sulfa drugs and their combinations against stationary phase B. burgdorferi, finding that some combinations are more effective than single drugs but less than a positive control.