Author

J. Fernandez-Martinez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:cryo-EM· 2 Approach:microscopy & imaging analysis· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Sali· 3 shared B. T. Chait· 2 shared D. Singh· 2 shared E. Villa· 2 shared I. Echeverria· 2 shared J. Wang· 2 shared M. P. Rout· 2 shared S. Suslov· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiophysics

A. Sali

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Molecular Architecture of the Nuclear Basket

D. Singh, N. Soni, J. Hutchings, I. Echeverria, F. Shaikh, M. Duquette, S. Suslov, Z. Li, T. van Eeuwen, K. Molloy, Y. Shi, J. Wang, Q. Guo, B. T. Chait, J. Fernandez-Martinez, , E. Villa

This study uses structural biology to reveal the architecture of the nuclear basket in yeast and mammals, showing how Mlp/Tpr proteins form its structural components.

bioRxiv · Mar 27, 2024Biophysics

Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress

L. Martinez-Ruiz, J. Florido, C. Rodriguez-Santana, A. Lopez-Rodriguez, A. Guerra-Librero, B. I. Fernandez-Gil, P. Garcia-Tarraga, J. M. Garcia-Verdugo, F. Oppel, H. Sudhoff, D. Sanchez-Porras, A. Ten-Esteve, J. Fernandez-Martinez, P. Gonzalez-Garcia, I. Rusanova, , G. Escames

This study shows that intratumoral melatonin injection enhances tumor regression in head and neck cancer models by increasing mitochondrial oxidative stress and improving cisplatin efficacy.

bioRxiv · Jul 17, 2023Cancer Biology

Dynamic molecular mechanism of the nuclear pore complex permeability barrier

T. Kozai, J. Fernandez-Martinez, T. van Eeuwen, P. Gallardo, L. E. Kapinos, A. Mazur, W. Zhang, J. Tempkin, R. Panatala, M. Delgado-Izquierdo, B. Raveh, A. Sali, B. T. Chait, L. M. Veenhoff, M. P. Rout, R. Y. H. Lim

The paper investigates the dynamic behavior of the nuclear pore complex permeability barrier in yeast, showing it functions as a dynamic polymer brush rather than a phase-separated condensate.

bioRxiv · Mar 31, 2023 · PreprintBiophysics

Comprehensive Structure and Functional Adaptations of the Yeast Nuclear Pore Complex

C. Akey, D. Singh, C. Ouch, I. Echeverria, I. Nudelman, J. M. Varberg, Z. Yu, F. Fang, Y. Shi, J. Wang, D. Saltzberg, K. Song, C. Xu, J. Gumbart, S. Suslov, , M. Rout

This study presents the structure of the yeast nuclear pore complex using cryo-EM, revealing its functional adaptations and evolutionary links.

bioRxiv · Oct 29, 2021Biophysics