Author

J. Humphrey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. B. Ramachandra· 1 shared A. H. Lippert· 1 shared A. M. Santos· 1 shared A. Winkel· 1 shared A. Yazdani· 1 shared B. Spronck· 1 shared C. Cavinato· 1 shared D. Klenerman· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBioengineering

A. B. Ramachandra

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Smooth Muscle Cell Death Drives an Osteochondrogenic Phenotype and Severe Proximal Vascular Disease in Progeria

S.-I. Murtada, Y. Kawamura, C. Cavinato, M. Wang, A. B. Ramachandra, B. Spronck, G. Tellides, J. Humphrey

This study links smooth muscle cell death to osteochondrogenic changes and vascular disease in progeria, identifying a sequence of pathological events leading to cardiovascular complications.

bioRxiv · Jan 10, 2023 · PreprintBioengineering

Robust T-cell signaling triggered on soft polydimethylsiloxane-supported lipid-bilayers

A. H. Lippert, I. B. Dimov, A. Winkel, J. McColl, J. Humphrey, K. Y. Chen, A. M. Santos, E. Jenkins, K. Franze, S. Davis, D. Klenerman

This study investigates T-cell signaling on soft lipid bilayers, finding early calcium signaling is not mechanosensitive but phosphatase exclusion occurs on soft substrates.

bioRxiv · Jun 5, 2020 · PreprintBiophysics

Data-driven Modeling of Thrombus Size and Shape in Aortic Dissections: Role of Hemodynamics

A. Yazdani, H. Li, M. Bersi, P. Di Achille, J. Insley, J. Humphrey, G. Karniadakis

This study develops a data-driven particle-continuum model to predict thrombus formation in aortic dissections, showing that geometry and hemodynamics influence thrombus size and distribution.

bioRxiv · Sep 12, 2017Bioengineering