Author

J. J. Song

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 2 Biochemistry· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. Steiner· 2 shared K.-H. Song· 2 shared M. A. Borden· 2 shared N. Ellens· 2 shared P. J. Martinez· 2 shared A. Green· 1 shared A. Kumar· 1 shared A. L. Green· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

J. Steiner

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Correlations of 276 missense variants of PSEN1, PSEN2, and APP on the production of Aβ peptides against variant effect predictors and biophysical structures

J. J. Song, Serina Yan, Sophia Liu, Adhvaith Sridhar, Kijung Sung, Joshua P. Pillai, Chengbiao Wu

This study correlates 276 missense variants in PSEN1, PSEN2, and APP with Aβ peptide levels and variant effect predictors to assess pathogenicity in early-onset Alzheimer's disease.

bioRxiv · Feb 11, 2026 · PreprintNeuroscience

Comprehensive Assessment of Blood-Brain Barrier Opening and Sterile Inflammatory Response: Unraveling the Therapeutic Window

P. J. Martinez, J. J. Song, F. G. Garay, K.-H. Song, T. Mufford, J. Steiner, J. DeSisto, N. Ellens, N. J. Serkova, A. L. Green, M. A. Borden

This study examines how microbubble volume doses and ultrasound mechanical indices affect BBB opening and sterile inflammation in mice, identifying a therapeutic window to optimize safe drug delivery.

bioRxiv · Oct 23, 2023Bioengineering

MRI-Guided Focused Ultrasound Blood-Brain Barrier Opening Increases Drug Delivery and Efficacy in a Diffuse Midline Glioma Mouse Model

P. J. Martinez, G. Nault, J. Steiner, M. F. Wempe, A. Pierce, B. Brunt, M. Slade, A. Mongin, J. J. Song, K.-H. Song, N. Ellens, N. Serkova, A. Green, M. A. Borden

MRI-guided focused ultrasound with microbubbles increases panobinostat delivery and efficacy in a diffuse midline glioma mouse model, reducing tumor volume and improving survival.

bioRxiv · Apr 5, 2023Bioengineering

DNMT1 inhibition by pUG-fold quadruplex RNA

L. I. Jansson-Fritzberg, C. I. Sousa, M. J. Smallegan, J. J. Song, A. R. Gooding, V. Kasinath, J. L. Rinn, T. R. Cech

This study shows that DNMT1 interacts with pUG-fold RNA, which inhibits its activity by blocking DNA binding.

bioRxiv · Oct 14, 2022Biochemistry

NAC1 Modulates Autoimmunity by Suppressing Regulatory T Cell- Mediated Tolerance

J.-M. Yang, Y. Ren, A. Kumar, X. Xiong, j. das, H.-y. Peng, L. Wang, X. Ren, R. C. Alainz, P. de Figueiredo, D. Fang, X. Liu, J. Wang, J. J. Song

This study shows NAC1 suppresses regulatory T cell-mediated tolerance by deacetylating and destabilizing FoxP3, leading to autoimmunity, and suggests targeting NAC1 could treat autoimmune disorders.

bioRxiv · Mar 1, 2022Immunology