Author

J. Kalfon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. E. Root· 2 shared A. Brown· 1 shared A. Fultineer· 1 shared A. Goodale· 1 shared A. Saadat· 1 shared D. M. Freed· 1 shared F. Vazquez· 1 shared I. Boyle· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

D. E. Root

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Author profile →

2 papers

Recent·Most cited

Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries

S. A. Misek, A. Fultineer, J. Kalfon, J. Noorbakhsh, I. Boyle, J. Dempster, L. Petronio, K. Huang, A. Saadat, T. Green, A. Brown, J. G. Doench, D. E. Root, J. McFarland, R. Beroukhim, J. S. Boehm

The paper identifies ancestry-related biases in CRISPR experiments caused by germline variants, showing disproportionate effects in cell models from recent African descent.

bioRxiv · Nov 18, 2022Cancer Biology

Mapping the landscape of genetic dependencies in chordoma

T. Sharifnia, M. J. Wawer, A. Goodale, Y. Lee, M. Kazachkova, J. M. Dempster, S. Muller, J. Levy, D. M. Freed, J. Sommer, J. Kalfon, F. Vazquez, W. C. Hahn, D. E. Root, P. A. Clemons, S. L. Schreiber

This study identifies essential genes in chordoma using CRISPR screens, revealing new therapeutic targets like PTPN11 and confirming known dependencies such as TBXT.

bioRxiv · Aug 17, 2022Cancer Biology