Arid5a mediates an IL-17-dependent pathway that drives autoimmunity but not antifungal host defense
T. C. Taylor, Y. Li, D.-D. Li, S. Majumder, M. J. McGeachy, P. S. Biswas, S. Gingras, S. Gaffen
This study shows Arid5a promotes IL-17-dependent autoimmunity but not antifungal immunity, suggesting targeted therapy could reduce autoimmune side effects.
bioRxiv · Feb 14, 2022Immunology