Author

J. P. Friedmann Angeli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

M. Conrad· 2 shared A. F. dos Santos· 1 shared A. Florez· 1 shared A. Przybylla· 1 shared A. Schulze· 1 shared A. Talebi· 1 shared A. Trumpp· 1 shared A.-C. Koenig· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

M. Conrad

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 17, 2022

Selenocysteine metabolism is a targetable vulnerability in MYCN-amplified cancers

H. Alborzy, Z. Chen, U. Yildiz…·J. P. Friedmann Angeli

This study identifies LRP8 as a targetable vulnerability in MYCN-amplified neuroblastoma by showing its role in selenocysteine import and resistance to ferroptosis.

DOI 10.1101/2022.05.17.492172

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 1, 2019

Cell density-dependent ferroptosis in breast cancer is induced by accumulation of polyunsaturated fatty acid-enriched triacylglycerides

E. Panzilius, F. Holstein, J. Dehairs…·C. H. Scheel

This study shows that low cell density in breast cancer cells increases ferroptosis sensitivity by promoting PUFA-enriched TAG accumulation and reducing lipid desaturation.

DOI 10.1101/417949

humanbulk RNA-seq

𝕏 PostBluesky