Author

J. Seibel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Pharmacology & Toxicology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

J. Fink· 2 shared M. Sauer· 2 shared N. Wolf· 2 shared T. Rudel· 2 shared A. Baluapuri· 1 shared A. Kuhlemann· 1 shared A. Kurz· 1 shared A. Mueller· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

J. Fink

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

The Legionella autoinducer LAI-1 is delivered by outer membrane vesicles to promote inter-bacterial and inter-kingdom signaling

M. Fan, P. Kiefer, P. Charki, C. Hedberg, J. Seibel, J. Vorholt, H. Hilbi

This paper identifies LAI-1 as a signaling molecule secreted by Legionella pneumophila via outer membrane vesicles, promoting inter-bacterial and inter-kingdom communication.

bioRxiv · Aug 22, 2023 · PreprintMicrobiology

Food interactions observed in a pharmacokinetic investigation comparing two marketed cold preparations (BNO1016 and ELOM-080) after administration to male beagle dogs

J. Seibel, A. Neumann, A. Mueller, M. Wonnemann

This study compares the pharmacokinetic effects of two cold remedies, BNO1016 and ELOM-080, under fasting and fed conditions in beagle dogs, finding no food effect for BNO1016 but significant food effects for ELOM-080.

bioRxiv · Aug 13, 2021 · PreprintPharmacology & Toxicology

In vitro screening of herbal medicinal products for their supportive curing potential in the context of SARS-CoV-2

H. Tran, P. Peterburs, J. Seibel, D. Abramov-Sommariva, E. Lamy

This study screens five herbal extracts for their potential to inhibit SARS-CoV-2 Spike-ACE2 interaction and modulate immune responses in vitro.

bioRxiv · Mar 1, 2021 · PreprintPharmacology & Toxicology

Concatemeric Broccoli reduces mRNA stability, aggregates and induces p-body formation

M. R. Rink, M. A. P. Baptista, T. Hennig, A. W. Whisnant, N. Wolf, J. Seibel, L. Dölken, J. B. Bosse

This study investigates the effects of Broccoli-aptamer concatemers on mRNA stability, aggregation, and p-body formation in different cellular contexts.

bioRxiv · Dec 7, 2020 · PreprintMicrobiology

Nanoscale imaging of bacterial infections by sphingolipid expansion microscopy

R. Goetz, T. C. Kunz, J. Fink, F. Solger, J. Schlegel, J. Seibel, V. Kozjak-Pavlovic, T. Rudel, M. Sauer

This study uses sphingolipid expansion microscopy to image bacterial infections at nanoscale resolution, revealing details of intracellular bacterial membranes previously only accessible via electron microscopy.

bioRxiv · May 6, 2020Microbiology

A central role of glutamine in Chlamydia infection

K. Rajeeve, N. Vollmuth, S. Janaki-Raman, T. Wulff, M. Schmalhofer, W. Schmitz, A. Baluapuri, C. Huber, J. Fink, F. R. Dejure, E. Wolf, W. Eisenreich, A. Schulze, J. Seibel, T. Rudel

This study identifies glutamine as essential for Chlamydia's EB-RB transition and shows that host glutamine metabolism is reprogrammed to support bacterial growth.

bioRxiv · Aug 27, 2019 · PreprintMicrobiology

Bioorthogonal labeling with tetrazine-dyes forsuper-resolution microscopy

G. Beliu, A. Kurz, A. Kuhlemann, L. Behringer-Pliess, N. Wolf, J. Seibel, Z.-D. Shi, M. Schnermann, J. Grimm, L. Lavis, S. Doose, M. Sauer

This study explores the use of tetrazine-dyes in super-resolution microscopy via Diels-Alder reactions with TCO-modified ncAAs, showing enhanced fluorescence and specific labeling capabilities.

bioRxiv · Dec 21, 2018Biochemistry