Author

J. Shenoy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Rizuan· 2 shared J. Mittal· 2 shared N. L. Fawzi· 2 shared P. Mohanty· 2 shared A. A. Hyman· 1 shared A. Honigmann· 1 shared A. Sergeeva· 1 shared D. Kuster· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCell Biology

A. Rizuan

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Author profile →

2 papers

Recent·Most cited

Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

X. Yan, D. Kuster, P. Mohanty, J. Nijssen, K. Pombo-Garcia, A. Rizuan, T. M. Franzmann, A. Sergeeva, P. M. dos Passos, L. George, S.-H. Wang, J. Shenoy, H. L. Danielson, A. Honigmann, Y. M. Ayala, , A. A. Hyman

This study shows that TDP-43 aggregation in stress granules requires up-concentration and oxidative stress, leading to intra-condensate demixing and pathological aggregates.

bioRxiv · Jan 23, 2024Cell Biology

Aliphatic residues contribute significantly to the phase separation of TDP-43 C-terminal domain

P. Mohanty, J. Shenoy, A. Rizuan, J. F. M. Ortiz, N. L. Fawzi, J. Mittal

This study identifies aliphatic residues as critical contributors to TDP-43 C-terminal domain phase separation, expanding the molecular understanding of protein phase separation.

bioRxiv · Nov 10, 2022 · PreprintBiophysics