Author

J. A. Ludwig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

A. J. Lazar· 3 shared S.-E. Lamhamedi-Cherradi· 3 shared B. A. Menegaz· 2 shared D. D. Truong· 2 shared D. R. Ingram· 2 shared H. C. Beird· 2 shared J. A. Livingston· 2 shared K. Rai· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. J. Lazar

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3 papers

Recent·Most cited

Dissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing

D. D. Truong, S.-E. Lamhamedi-Cherradi, R. W. Porter, S. Krishnan, J. Swaminathan, A. Gibson, A. J. Lazar, J. A. Livingston, V. Gopalakrishnan, N. Gordon, N. C. Daw, R. Gorlick, J. A. Ludwig

The paper shows that dissociation methods bias transcriptomes in sarcoma single-cell and single-nucleus RNA-seq, and demonstrates computational correction of these biases.

bioRxiv · Jan 21, 2022 · PreprintCancer Biology

The Androgen Receptor: A Therapeutic Target in Desmoplastic Small Round Cell Sarcoma

S.-E. Lamhamedi-Cherradi, M. Maitituoheti, B. A. Menegaz, S. Krishnan, A. M. Vetter, P. Camacho, C.-C. Wu, H. C. Beird, R. W. Porter, D. R. Ingram, V. Ramamoorthy, S. Mohiuddin, D. McCall, D. D. Truong, B. Cuglievan, , J. A. Ludwig

The paper shows that DSRCT is driven by the androgen receptor and responds to androgen deprivation therapy.

bioRxiv · Jan 20, 2022Cancer Biology

New cellular models of undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumor

A. D. Bhalla, S. M. Landers, A. K. Singh, M. G. Yeagley, G. S. B. Meyerson, Z. A. Mulder, C. B. Delgado-Baez, S. Dunnand, V. Kochat, K. J. Tomczak, T. Nguyen, X. Ma, S. Bolshakov, B. A. Menegaz, S.-E. Lamhamedi-Cherradi, , K. E. Torres

This study generates new cell lines for undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumor to better study sarcomagenesis and develop therapies.

bioRxiv · May 13, 2021 · PreprintCancer Biology