Author

R. Gorlick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

A. Ferrena· 1 shared A. Gibson· 1 shared A. J. Lazar· 1 shared A. Singla· 1 shared B. H. Hoang· 1 shared D. D. Truong· 1 shared D. S. Geller· 1 shared D. Zheng· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Ferrena

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2 papers

Recent·Most cited

Targeted inhibition of SCF-SKP2 confers anti-tumor activities resulting in a survival benefit in osteosarcoma

J. Wang, A. Ferrena, S. Singh, V. Viscarret, W. Al-Hardan, O. Aldahamsheh, H. Borjihan, A. Singla, S. Yaguare, J. Tingling, X. Zi, Y. Lo, R. Gorlick, E. L. Schwartz, H. Zhao, , B. H. Hoang

This study shows that inhibiting SKP2 in osteosarcoma reduces tumor growth and improves survival, suggesting it as a potential therapeutic target.

bioRxiv · May 13, 2023 · PreprintCancer Biology

Dissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing

D. D. Truong, S.-E. Lamhamedi-Cherradi, R. W. Porter, S. Krishnan, J. Swaminathan, A. Gibson, A. J. Lazar, J. A. Livingston, V. Gopalakrishnan, N. Gordon, N. C. Daw, R. Gorlick, J. A. Ludwig

The paper shows that dissociation methods bias transcriptomes in sarcoma single-cell and single-nucleus RNA-seq, and demonstrates computational correction of these biases.

bioRxiv · Jan 21, 2022 · PreprintCancer Biology