Author

J. V. Busik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. L. Longhini· 2 shared B. Asare-Bediako· 2 shared C. P. Vieira· 2 shared M. B. Grant· 2 shared M. Dupont· 2 shared M. S. Sielski· 2 shared S. S. Hammer· 2 shared T. Lydic· 2 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

A. L. Longhini

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2 papers

Recent·Most cited

Selective LXR agonist, DMHCA, corrects the retina-bone marrow axis in type 2 diabetes

C. P. Vieira, S. D. Fortmann, M. Hossain, A. L. Longhini, S. S. Hammer, B. Asare-Bediako, D. K. Crossman, M. S. Sielski, Y. Adu-Agyeiwaah, M. Dupont, J. L. Floyd, S. Li Calzi, T. Lydic, R. S. Welner, G. J. Blanchard, , M. B. Grant

This study shows that DMHCA, a selective LXR agonist, corrects the retina-bone marrow axis in type 2 diabetes by restoring retinal function, cholesterol homeostasis, and hematopoietic stem cell balance.

bioRxiv · Feb 11, 2020 · PreprintCell Biology

Pharmacological and fasting-induced activation of SIRT1/LXRα signaling alleviates diabetes-induced retinopathy.

S. S. Hammer, C. P. Vieira, D. McFarland, M. Sandler, Y. Levitsky, T. F. Dorweiler, T. Lydic, B. Asare-Bediako, Y. Adu-Agyeiwaah, M. S. Sielski, M. Dupont, A. L. Longhini, S. L. Calzi, D. Chakraborty, G. M. Seigel, , J. V. Busik

This study shows that activating SIRT1 signaling through fasting or pharmacology reduces diabetes-induced retinopathy by improving cholesterol metabolism, reducing inflammation, and preserving neural function.

bioRxiv · Dec 10, 2019 · PreprintCell Biology