Author

M. B. Grant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C. P. Vieira· 3 shared M. DuPont· 3 shared S. D. Fortmann· 3 shared A. L. Longhini· 2 shared B. Asare-Bediako· 2 shared J. L. Floyd· 2 shared J. V. Busik· 2 shared M. S. Sielski· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

C. P. Vieira

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Fixation Before Dissociation Using a Deep Eutectic Solvent Preserves In Vivo States and Phospho-Signaling in Single-Cell Sequencing

S. D. Fortmann, B. F. Frey, V. S. Hanumanthu, S. Liu, A. Goldsborough, K. V. Kilchrist, P. B. Ferrell, C. T. Weaver, M. B. Grant, R. S. Welner

This study introduces a deep eutectic solvent fixation method that preserves in vivo cellular states and phospho-signaling for scRNA-seq, enabling the identification of hyperactivated Th17 T cells.

bioRxiv · Feb 13, 2023 · PreprintImmunology

Plasma microbiome in COVID-19 subjects: an indicator of gut barrier defects and dysbiosis

R. Prasad, M. J. Patton, J. L. Floyd, C. P. Vieira, S. D. Fortmann, M. DuPont, A. Harbour, J. R. Chen See, J. Wright, R. Lamendella, B. R. Stevens, M. B. Grant

The paper analyzes plasma microbiome and permeability markers in COVID-19 patients and healthy controls, finding higher gut permeability and gram-negative bacteria abundance in patients.

bioRxiv · Apr 6, 2021 · PreprintMicrobiology

Selective LXR agonist, DMHCA, corrects the retina-bone marrow axis in type 2 diabetes

C. P. Vieira, S. D. Fortmann, M. Hossain, A. L. Longhini, S. S. Hammer, B. Asare-Bediako, D. K. Crossman, M. S. Sielski, Y. Adu-Agyeiwaah, M. Dupont, J. L. Floyd, S. Li Calzi, T. Lydic, R. S. Welner, G. J. Blanchard, , M. B. Grant

This study shows that DMHCA, a selective LXR agonist, corrects the retina-bone marrow axis in type 2 diabetes by restoring retinal function, cholesterol homeostasis, and hematopoietic stem cell balance.

bioRxiv · Feb 11, 2020 · PreprintCell Biology

Pharmacological and fasting-induced activation of SIRT1/LXRα signaling alleviates diabetes-induced retinopathy.

S. S. Hammer, C. P. Vieira, D. McFarland, M. Sandler, Y. Levitsky, T. F. Dorweiler, T. Lydic, B. Asare-Bediako, Y. Adu-Agyeiwaah, M. S. Sielski, M. Dupont, A. L. Longhini, S. L. Calzi, D. Chakraborty, G. M. Seigel, , J. V. Busik

This study shows that activating SIRT1 signaling through fasting or pharmacology reduces diabetes-induced retinopathy by improving cholesterol metabolism, reducing inflammation, and preserving neural function.

bioRxiv · Dec 10, 2019 · PreprintCell Biology