Author

J.-C. Tardif

Primary ORCID profile (0000-0001-5991-4366 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

J.-C. TardifiD1 paper · Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Physiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Assay:multiome· 2

Frequent Co-Authors

B. G. Allen· 5 shared F. Sahmi· 4 shared J. Trepanier· 4 shared P. Sahadevan· 4 shared S. A. Nawaito· 4 shared Y. Shi· 4 shared M. G. Sirois· 3 shared M. Gaestel· 3 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersCell Biology

B. G. Allen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ERK3 Is Involved in Regulating Cardiac Fibroblast Function

P. Sahadevan, D. Dingar, S. A. Nawaito, R. S. Nair, J. Trepanier, F. Sahmi, Y. Shi, M.-A. Gillis, M. G. Sirois, S. Meloche, J.-C. Tardif, B. G. Allen

This study shows ERK3 regulates cardiac fibroblast function by affecting collagen production and motility in response to TGF-β and TAC.

bioRxiv · Dec 5, 2023Cell Biology

MK2 deficiency decreases mortality during the inflammatory phase after myocardial infarction in mice

J. Trepanier, S. A. Nawaito, P. Sahadevan, F. Sahmi, N. Duquette, D. Gelinas, M.-A. Gillis, Y. Shi, C. Torok, M.-E. Clavet-Lanthier, M. Gaestel, M. G. Sirois, J.-C. Tardif, B. G. Allen

This study shows MK2 deficiency reduces mortality and alters cytokine levels during the inflammatory phase after myocardial infarction in mice.

bioRxiv · Mar 6, 2023 · PreprintPhysiology

MK2-deficient mice are bradycardic and display delayed hypertrophic remodelling in response to a chronic increase in afterload

M. Ruiz, M. Khairallah, D. Dingar, G. Vaniotis, R. J. Khairallah, B. Lauzier, S. Thibault, J. Trepanier, Y. Shi, A. Douillette, B. Hussein, S. A. Nawaito, P. Sahadevan, A. Nguyen, M.-A. Gillis, , B. G. Allen

This study examines the cardiac phenotype of MK2-deficient mice, finding altered autonomic regulation, increased metabolic gene expression, reduced mitochondrial Ca2+-sensitivity, and delayed hypertrophic remodeling in response to pressure overload.

Journal of the American Heart Association · Feb 16, 2021Peer-reviewedPhysiology

Expression, subcellular localization, and phosphorylation of MK5 in adult cardiac ventricular fibroblasts

P. Sahadevan, S. A. Nawaito, J. Trepanier, S. Benamar, F. Sahmi, G. Theberge-Julien, L. R. Villeneuve, M. Gaestel, J.-C. Tardif, B. G. Allen

This study investigates MK5 expression, localization, and phosphorylation in cardiac myofibroblasts and myocytes, finding that p38/{beta} mediates T182-MK5 phosphorylation and activation.

bioRxiv · Jul 24, 2020 · PreprintBiochemistry

Protein Tyrosine Phosphatase 1B Regulates MicroRNA-208b-Argonaute 2 Association and Thyroid Hormone Responsiveness in Cardiac Hypertrophy

G. Coulis, Y. Shi, D. P. Labbe, A. Bergeron, F. Sahmi, V. Vinette, G. Karsenty, B. G. Allen, M. Tremblay, J.-C. Tardif, B. Boivin

This study shows that PTP1B inactivation disrupts miR-208b-Argonaute 2 interaction, leading to increased THRAP1 expression and thyroid hormone-induced cardiac hypertrophy.

bioRxiv · Sep 10, 2019 · PreprintCell Biology