Author

J.-L. Li

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

X. Li· 2 shared X. Xu· 2 shared Y. Zhang· 2 shared A. G. T. Pyo· 1 shared A. Gleiberman· 1 shared A. Solis· 1 shared A. V. Gudkov· 1 shared A. Waddell· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

X. Li

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Toll-Like-Receptor 5 protects against pulmonary fibrosis by reducing lung dysbiosis

A. Gleiberman, R. Invernizzi, P. L. Molyneaux, B. G. Wu, Y. Lipinski, M. Kugler, L. N. Segal, Y. Sakamachi, E. Wiley, A. Solis, C. G. Johnson, X. Meng, J. Malphurs, B. Papas, S. Mehta, , N. Kaminski

TLR5 deficiency is linked to pulmonary fibrosis due to its role in preventing microbial dysbiosis following lung injury.

bioRxiv · Apr 30, 2024 · PreprintImmunology

Effects of linker length on phase separation: lessons from the Rubisco-EPYC1 system of the algal pyrenoid

T. GrandPre, Y. Zhang, A. G. T. Pyo, B. Weiner, J.-L. Li, M. C. Jonikas, N. S. Wingreen

The paper investigates how linker length affects phase separation in the Rubisco-EPYC1 system of green algae, finding that shorter linkers significantly reduce critical concentrations.

bioRxiv · Jun 11, 2023 · PreprintBiophysics

Dietary methionine restriction impairs anti-tumor immunity through gut microbiota

M. Ji, X. Xu, Q. Xu, X. Xu, M. A. Azcarate-Peril, X. Wu, J. Liu, J. W. Locasale, J.-L. Li, I. Shats, X. Li

This study shows that dietary methionine restriction worsens cancer growth and reduces anti-tumor immunity via gut microbiota and immune suppression in immunocompetent mice.

bioRxiv · Aug 27, 2021 · PreprintCancer Biology

SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc- SMPDL3B

X. Li, W. Fan, S. Tang, X. Fan, Y. Fang, X. Xu, L. Li, J. Xu, J.-L. Li, Z. Wang

This study identifies SIRT1's role in regulating sphingolipid metabolism and neural differentiation in mESCs via c-Myc and SMPDL3B, suggesting therapeutic potential for neurological diseases.

eLife · May 27, 2021Peer-reviewedCell Biology

The DAXX-SREBP axis promotes oncogenic lipogenesis and tumorigenesis

I. Mahmud, G. Tian, J. Wang, J. Lewis, A. Waddell, M. L. Lydon, L. Y. Zhao, J.-L. Li, H. T. Purayil, Z. Huo, Y. Daaka, T. J. Garrett, D. Liao

This study identifies the DAXX-SREBP axis as a driver of lipogenesis and tumorigenesis by showing its role in activating lipogenic gene expression and promoting tumor growth.

bioRxiv · Dec 31, 2020 · PreprintCancer Biology