Author

J.-X. Qu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

L. Liu· 2 shared L. Yang· 2 shared S. Han· 2 shared X. Duan· 2 shared Y. Liu· 2 shared Y. Zhang· 2 shared Z. Cai· 2 shared Z. Jiang· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

L. Liu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nosocomial Pseudomonas aeruginosaregulates alginate biosynthesis and Type VI secretion system during adaptive and convergent evolution for coinfection in critically ill COVID-19 patients

J.-X. Qu, Z. Cai, X. Duan, H. Zhang, S. Han, K. Yu, Z. Jiang, Y. Zhang, Y. Liu, Y. Liu, L. Liu, L. Yang

This study investigates how Pseudomonas aeruginosa adapts and evolves during coinfection with COVID-19, showing it overexpresses alginate and reduces Type VI secretion system to enhance biofilm formation and suppress virulence.

bioRxiv · Apr 9, 2021 · PreprintMicrobiology

Persistent bacterial coinfection of a COVID-19 patient caused by a genetically adapted Pseudomonas aeruginosa chronic colonizer

J.-X. Qu, Z. Cai, Y. Liu, X. Duan, S. Han, Y. Zhu, Z. Jiang, Y. Zhang, C. Zhuo, Y. Liu, Y. Liu, L. Liu, L. Yang

The paper describes a genetically adapted Pseudomonas aeruginosa small colony variant causing persistent bacterial coinfection in a COVID-19 patient, showing enhanced biofilm formation and quorum sensing.

bioRxiv · Aug 5, 2020Microbiology

Modulating pathogenesis with Mobile-CRISPRi

O. Rosenberg, J.-X. Qu, N. K. Prasad, J. Peters, M. Looney, M. Yu, A. Lyden, S. Chen, E. Crawford, M. Silvis

The paper demonstrates the use of Mobile-CRISPRi to knock down virulence life-style genes in a murine infection model, showing reduced virulence in mice.

bioRxiv · Apr 25, 2019Microbiology