Author

Jaco C. Knol

Amsterdam University Medical Centers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1

Frequent Co-Authors

Connie R. JiméneziD· 3 shared Alex A. HennemaniD· 2 shared Sander R. PiersmaiD· 2 shared Thang V. PhamiD· 2 shared Aaron FrankliniD· 1 shared Alexander SpeeriD· 1 shared Andrea BertottiiD· 1 shared Carolien van AlpheniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMicrobiology

Connie R. JiménezORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis

Robin Lissner, Aaron Franklin, Samuel T. Benedict, Vicky Charitou, Alexander Speer, Jaco C. Knol, Connie R. Jiménez, Patrick Joseph Moynihan, Sergey Nejentsev, Coenraad P. Kuijl, Wilbert Bitter

This study identifies lipoproteins LpqZ and FecB as essential for mycobacterial cell envelope biogenesis through interactions with enzymes involved in glycoconjugate synthesis.

mBio · Dec 12, 2025Peer-reviewedMicrobiology

NUAK1 regulates contraction in vascular smooth muscle cells derived from abdominal aortic aneurysm patients

Karlijn B. Rombouts, Tara A. R. van Merrienboer, Alex A. Henneman, Jaco C. Knol, Thang V. Pham, Sander R. Piersma, Connie R. Jiménez, Peter Lodewijk Hordijk, Jolanda van der Velden, Natalija Bogunovic, Kak Khee Yeung

This study identifies NUAK1 as a regulator of vascular smooth muscle cell contraction in abdominal aortic aneurysm patients, showing its role in modulating MYPT1 activity and contraction-related proteins.

bioRxiv · Dec 19, 2024 · PreprintCell Biology

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active phosphokinases

Robin Beekhof, Carolien van Alphen, Alex A. Henneman, Jaco C. Knol, Thang V. Pham, Frank Rolfs, Mariëtte Labots, Evan Henneberry, Tessa Y. S. Le Large, Richard R. de Haas, Sander R. Piersma, Valentina Vurchio, Andrea Bertotti, Livio Trusolino, Henk M.W. Verheul, Connie R. Jiménez

INKA identifies active phosphokinases in cancer by integrating kinase and substrate phosphorylation data from phosphoproteomics.

Molecular Systems Biology · Apr 1, 2019Peer-reviewedSystems Biology