Author

James K. Martin

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander MuiriD· 1 shared Alica K. MichelsiD· 1 shared Anika T. Thomas-TothiD· 1 shared Christopher J. HalbrookiD· 1 shared Christopher R. WeberiD· 1 shared Colin S. SheehaniD· 1 shared Darby AgovinoiD· 1 shared Grace Croley· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander MuirORCID

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1 paper

Recent·Most cited

Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer

Colin S. Sheehan, Lyndon Hu, Guillaume Cognet, Grace Croley, Thao Trang Nguyen, Anika T. Thomas-Toth, Darby Agovino, Patrick B. Jonker, Mumina Sadullozoda, Leah M. Ziolkowski, James K. Martin, Alica K. Michels, Ranya Dano, Mohammed A. Khan, Rasangi Perera, , Alexander Muir

This study shows that pancreatic cancer cells in a nutrient-stressed tumor microenvironment develop drug tolerance, and identifies BCL-XL inhibition as a potential therapeutic strategy.

bioRxiv · Sep 4, 2025 · PreprintCancer Biology