Author

Jane Xie

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrián Holguín-HorcajoiD· 1 shared Alexander C VostaliD· 1 shared Andy A. Patamawenu· 1 shared Anna Hostal· 1 shared Ben Z. StangeriD· 1 shared Breanna KimiD· 1 shared Ceanna Cooney· 1 shared Daniel C. DouekiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Adrián Holguín-HorcajoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Intranasal Replicating Adenovirus type 4-SARS-CoV-2 Recombinants Induce Superior Immune Response Durability and Efficacy in Preclinical Testing Compared to Standard Intramuscular Vaccines

Breanna Kim, Rachel Roenicke, P J Roeder, Isabel Steinberg, Andy A. Patamawenu, Mitra Harrison, Freya van't Veer, Emma Koory, Jane Xie, Tulley Shofner, Kenta Matsuda, Eleanor Wettstein, Ellison Ober, Ceanna Cooney, Tae Sung Kim, , Mark Connors

This study compares intranasal and intramuscular vaccines, finding that the intranasal Ad4-S vaccine provides more durable and effective immune responses against SARS-CoV-2 in preclinical models.

bioRxiv · Feb 5, 2026 · PreprintImmunology

Identification and Implications for Tumor Heterogeneity of a DNA Methylation-Based Signature Classifying Pancreatic Ductal Adenocarcinoma Based on their Cellular Origin

Ilianna Zoi, Memoona Rajput, Adrián Holguín-Horcajo, Malak Haidar, Davide Brusa, Ken Chu, Jane Xie, Mario A. Shields, Sofia Ferreira, Ben Z. Stanger, Laura Donatella Attardi, Janel L. Kopp, Marc P. Stemmler, Rémy Nicolle, Meritxell Rovira, Patrick Jacquemin

This study identifies a DNA methylation signature preserved during pancreatic carcinogenesis that distinguishes PDAC origins and influences tumor behavior.

bioRxiv · Mar 7, 2025 · PreprintCancer Biology