Author

Jasleen Singh

Indiana University BloomingtonPrimary ORCID profile (0009-0009-0679-7499 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Jasleen SinghiD1 paper · Howard Hughes Medical Institute

Biology Disciplines

Click to filter author papers

Molecular Biology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:plant (other)· 4 Organism:Arabidopsis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Craig S. PikaardiD· 5 shared Akihito FukudomeiD· 2 shared Feng WangiD· 2 shared Jered M. WendteiD· 2 shared Jeremy R. Haag· 2 shared Olga Pontes· 2 shared Vibhor MishraiD· 2 shared Anastasia McKinlayiD· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersMolecular Biology

Craig S. PikaardORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Enzymatic reactions of AGO4 in RNA-directed DNA methylation: siRNA duplex loading, passenger strand elimination, target RNA slicing and sliced target retention

Feng Wang, Hsiao‐Yun Huang, Jie Huang, Jasleen Singh, Craig S. Pikaard

The paper shows that AGO4 slicing of 23 nt passenger strands and retention of sliced target RNAs enhances RNA-directed DNA methylation in plants.

bioRxiv · Oct 6, 2022Molecular Biology

A DCL3 dicing code within Pol IV-RDR2 transcripts diversifies the siRNA pool guiding RNA-directed DNA methylation

Andrew Loffer, Jasleen Singh, Akihito Fukudome, Vibhor Mishra, Feng Wang, Craig S. Pikaard

The paper shows that Pol IV and RDR2 transcript features determine siRNA size, sequence, and strand polarity, enhancing DNA methylation coverage.

eLife · Jan 31, 2022Peer-reviewedMolecular Biology

Structure and RNA template requirements of Arabidopsis RNA-DEPENDENT RNA POLYMERASE 2

Akihito Fukudome, Jasleen Singh, Vibhor Mishra, Eswar R. Reddem, Francisco Martínez-Márquez, Sabine Wenzel, Rui Yan, Momoko Shiozaki, Zhiheng Yu, Joseph Che‐Yen Wang, Yuichiro Takagi, Craig S. Pikaard

This paper reports the structure of Arabidopsis RDR2 and shows how it initiates transcription from RNA templates displaced from RNA-DNA hybrids.

Proceedings of the National Academy of Sciences · Dec 13, 2021Peer-reviewedMolecular Biology

siRNA biogenesis, DNA methylation and target locus silencing are distinct and separable Pol IV sub-functions differentially dependent on the largest subunit's CTD

Jered M. Wendte, Jeremy R. Haag, Olga Pontes, Jasleen Singh, Sara Metcalf, Craig S. Pikaard

The paper shows that the CTD of NRPD1 is critical for siRNA production and target locus silencing but not for DNA methylation, indicating distinct roles for Pol IV in RdDM.

Nucleic Acids Research · Jul 5, 2019Peer-reviewedMolecular Biology

Functional dissection of the Pol V large subunit CTD in RNA-directed DNA methylation

Jered M. Wendte, Jeremy R. Haag, Jasleen Singh, Anastasia McKinlay, Olga Pontes, Craig S. Pikaard

The paper investigates the role of the Pol V CTD in RNA-directed DNA methylation, showing its necessity for in vivo function and its interaction with RRP6L1.

Cell Reports · Jun 1, 2017Peer-reviewedMolecular Biology