Jeroen P. J. Saeij

This study shows that Vγ9Vδ2 T cells detect Toxoplasma gondii via phosphoantigens, activate NK cells, and drive early IFNγ production in humans.

This study identifies TgWIP interactions with Nck1/Grb2 and the WAVE complex to reveal how Toxoplasma manipulates host cell actin dynamics and motility.

This study identifies how Toxoplasma gondii uses GRA effectors to manipulate host signaling and chromatin accessibility, promoting macrophage migration and parasite dissemination.

This paper identifies GRA47 and GRA72 as Toxoplasma gondii pore-forming proteins that regulate small molecule permeability of the parasitophorous vacuole, with mutations affecting their function and virulence.