Jian Wang

The paper presents the HLA Ligand Atlas, a resource of HLA-I and -II ligands from benign tissues, showing tissue and individual differences and non-canonical ligand origins.

This study shows FGF2 improves synaptic pathology in MHE by increasing NRG1 and ErbB4 signaling, enhancing synapse activity and dendritic spine density through Sirt1.

PALM-Seq simultaneously sequences cell-free long and small RNA, identifying pregnancy-related RNAs and sample-specific signatures in plasma, amniotic fluid, leukocytes, and placentas.

The paper analyzes single-cell RNA-seq data from human embryos to compare gene expression between males and females, identifying differences in sex chromosome activation and dosage compensation during early development.

The paper resolves the sex-determination system in Ginkgo biloba, identifying XY chromosomes and five potential sex-determination genes originating ~14 million years ago.

This study investigates whether mitochondrial DNA content can predict embryo viability and finds no significant association with chromosome status or other factors.

This study identifies 15 hub genes in breast cancer through integrated bioinformatics analysis and finds their higher expression correlates with shorter overall survival.

The paper analyzes recombination patterns in Escherichia coli genomes to show extensive intra-clade recombination and reduced inter-clade recombination, establishing genetic barriers between subpopulations.