Author

Jie Shen

Army Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Aaron R. WinkleriD· 1 shared Amanda O. ChaniD· 1 shared Blake E. SmithiD· 1 shared Caleb R. PereziD· 1 shared Ce DouiD· 1 shared Chirag KrishnaiD· 1 shared ChunBo ZengiD· 1 shared Connor S. DobsoniD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperImmunology

Aaron R. WinklerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Efferocytosis Remodels Osteoclast Metabolism and Enhances Antibacterial Defense

Qixiu Yu, Jie Zhang, Ying Qu, Yong Tang, Yuyang Zhang, Yewei Jia, Qijie Dai, Zhoukai Huang, Jie Shen, Nathachit Limjunyawong, Fei Luo, Ce Dou

This study shows that osteoclast efferocytosis enhances antibacterial defense by remodeling metabolism through glycolytic activity and lactate handling.

bioRxiv · Oct 16, 2026 · PreprintCell Biology

Macrophage Antigen Presentation Is Unleashed by Pan-RAS Inhibition to Promote Antitumor Immunity

Jie Shen, Weini Li, Xin He, Lianjun Zhang, Huidi Shucheng, ChunBo Zeng, Mingtian Che, Wei Fan, Suda Jo, Heping Yang, Yuan Yu, Zakir Khan, Zhi Chen, DuoYao Cao

This paper shows that pan-RAS inhibition enhances macrophage antigen presentation, promoting antitumor immunity in RAS-wild-type tumors through epigenetic modulation of NLRC5.

bioRxiv · Feb 2, 2026 · PreprintImmunology

Scalable TCR synthesis and screening enables antigen reactivity mapping in vitiligo

Stephanie A. Gaglione, Rachit S Mukkamala, Chirag Krishna, Blake E. Smith, Marc H. Wadsworth, Scott A. Jelinsky, Caleb R. Perez, Laura Schmidt-Hong, Erica L. Katz, Kyle J. Gellatly, Lestat R. Ali, Jie Shen, Patrick V. Holec, Qingyang Henry Zhao, Amanda O. Chan, , Michael E. Birnbaum

The paper introduces a scalable TCR synthesis and screening method, TCRAFT, to map antigen reactivity in vitiligo and pancreatic ductal adenocarcinoma.

Immunity · Jan 28, 2026Peer-reviewedImmunology