Oxytocin Modulation of Spinal Circuits Drives Therapeutic Benefits of Massage
Manon Bohic, Paula Salamone, Wanhong Zuo, Ahmed Negm, Sasha L. Fulton, Shibin Du, Swathi Jayakumar, Jessica Keating, Vanessa Soubeyre, Mark A. Gradwell, A. Upadhyay, Lucero Shorter, Joel Kim, Yukiko Inoue, Takayoshi Inoue, , Victoria E. Abraira
This study shows that massage triggers oxytocin release, which modulates spinal circuits to enhance well-being and reduce pain through a shared mechanism.
bioRxiv · Mar 3, 2026 · PreprintNeuroscience