Author

Dragoş Niculescu

Aarhus University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra RebsamiD· 1 shared Anders NykjæriD· 1 shared Angelo IannielliiD· 1 shared Célia VasliniD· 1 shared Ekin Ucuncu· 1 shared Fabia FebbraroiD· 1 shared Franck MaurinotiD· 1 shared Ida Hyllen KlæstrupiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Alexandra RebsamORCID

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2 papers

Recent·Most cited

Enhanced Production of Mesencephalic Dopaminergic Neurons from Lineage-Restricted Human Undifferentiated Stem Cells

Muyesier Maimaitili, Muwan Chen, Fabia Febbraro, Ekin Ucuncu, Rachel L. Kelly, Jonathan C. Niclis, Josefine Rågård Christiansen, Noëmie Mermet-Joret, Dragoş Niculescu, Johanne Lauritsen, Angelo Iannielli, Ida Hyllen Klæstrup, Uffe Birk Jensen, Per Qvist, Sadegh Nabavi, , Mark Denham

This study genetically modifies human pluripotent stem cells to generate lineage-restricted undifferentiated stem cells that efficiently produce mesencephalic dopaminergic neurons for potential clinical applications.

Nature Communications · Dec 5, 2023Peer-reviewedNeuroscience

Direct readout of neural stem cell transgenesis with an integration-coupled gene expression switch

Takuma Kumamoto, Franck Maurinot, Raphaëlle Barry‐Martinet, Célia Vaslin, Sandrine Vandormael‐Pournin, Mickaël Le, Marion Lerat, Dragoş Niculescu, Michel Cohen‐Tannoudji, Alexandra Rebsam, Karine Loulier, Stéphane Nedelec, Samuel Tozer, Jean Livet

This paper introduces a genetic switch called iOn that enables the identification of genomic integration events by triggering gene expression upon insertion, improving transgenesis in stem cells and model organisms.

Neuron · Jun 18, 2020Peer-reviewedDevelopmental Biology