Author

John Alexander

Democritus University of Thrace

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Alisa ZverevaiD· 1 shared Andrea GillespieiD· 1 shared Andrew P. BarbouriD· 1 shared Angelika ReineriD· 1 shared Anna TrigosiD· 1 shared Christoph BockiD· 1 shared Christopher J. LordiD· 1 shared Cuong Phu Duong· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Alisa ZverevaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Functional annotation of breast cancer risk loci implicates perturbation of FILIP1L expression in mammary fibroblasts in influencing breast cancer risk.

Alisa Zvereva, Harriet Kemp, Andrea Gillespie, Katarzyna Tomczyk, Shirleny Romualdo Cardoso, Selin Sevgi, Kate Mackie, Vita Fedele, John Alexander, Iain Goulding, Jenny Gomm, J Louise Jones, Joseph S. Baxter, Stephen J. Pettitt, Christopher J. Lord, , Nichola Johnson

The paper identifies a breast cancer risk locus by analyzing functional variants and target genes in mammary fibroblasts, showing their non-autonomous impact on breast cancer risk.

medRxiv · Apr 10, 2026 · PreprintGenetic & Genomic Medicine

SMAD4 loss drives chromosomal instability during tumourigenesis via translational reprogramming

Julia V. Milne, Kameng Wu, Eric P. Kusnadi, Sandra Brosda, Kenji Mark Fujihara, Ebtihal H Mustafa, Sasha Witts, Katherine Papastratos, Maree Pechlivanis, Anna Trigos, Metta K. Jana, Paul J. McMillan, Thomas Daniel Jackson, Niko Thio, Yuzhou Feng, , Nicholas James Clemons

This study shows SMAD4 loss reprograms translation to induce chromosomal instability, driving tumourigenesis, and identifies CDK11B-p58 as a key mediator.

bioRxiv · Mar 25, 2026 · PreprintCancer Biology

TECPR2 a positive regulator of autophagy is implicated in healthy brain ageing

John Alexander, Thomas Ströbel, Marianthi Georgitsi, Michael K. Schuster, Thomas Penz, Christoph Bock, Selma Hönigschnabl, Angelika Reiner, Peter A. Fischer, Peristera Paschou, Gábor Géza Kovács

The paper identifies a genetic variant in TECPR2 associated with healthy brain aging and neuroprotection against Alzheimer's disease.

bioRxiv · Jun 30, 2017 · PreprintGenomics