Author

Thomas Penz

Austrian Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Christoph BockiD· 3 shared Andreas LackneriD· 1 shared Andreas W. ThomaeiD· 1 shared Angelika ReineriD· 1 shared Axel Pilz· 1 shared Christa BueckeriD· 1 shared Dirk BaumjohanniD· 1 shared Elena Sergeevna KotovaiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

Christoph BockORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanical Centrosome Fracturing during Cell Navigation

Madeleine T. Schmitt, Janina Kroll, Mauricio J.A. Ruiz-Fernandez, Robert Hauschild, Shaunak Ghosh, Petra Kameritsch, Jack Merrin, Johanna Schmid, Kasia Stefanowski, Andreas W. Thomae, Jingyuan Cheng, Gamze Naz Öztan, Peter Konopka, Germán Camargo Ortega, Thomas Penz, , Jörg Renkawitz

The paper shows that centrosomes in non-dividing cells can fracture under mechanical stress during cell navigation, and Dyrk3 prevents this fracturing to maintain cellular function.

Science Advances · Apr 25, 2025Peer-reviewedCell Biology

Detailed temporal dissection of an enhancer cluster reveals two distinct roles for individual elements

Henry Thomas, Elena Sergeevna Kotova, Swathi Jayaram, Axel Pilz, Merrit Romeike, Andreas Lackner, Thomas Penz, Christoph Bock, Martin Leeb, Florian Halbritter, Joanna Wysocka, Christa Buecker

The paper identifies an enhancer element that amplifies Fgf5 expression by accumulating paused RNA Polymerase II, revealing a new mechanism of enhancer collaboration during differentiation.

Molecular Cell · Jan 21, 2021Peer-reviewedMolecular Biology

TECPR2 a positive regulator of autophagy is implicated in healthy brain ageing

John Alexander, Thomas Ströbel, Marianthi Georgitsi, Michael K. Schuster, Thomas Penz, Christoph Bock, Selma Hönigschnabl, Angelika Reiner, Peter A. Fischer, Peristera Paschou, Gábor Géza Kovács

The paper identifies a genetic variant in TECPR2 associated with healthy brain aging and neuroprotection against Alzheimer's disease.

bioRxiv · Jun 30, 2017 · PreprintGenomics