Author

Jonas Brill

Goethe University Frankfurt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Andre SchwarziD· 1 shared Danielle Ann GrotjahniD· 1 shared Delong LiiD· 1 shared Dietmar HammerschmidiD· 1 shared Erin Margaret SchumaniD· 1 shared Felix KrausiD· 1 shared Florian WilflingiD· 1 shared Gerhard HummeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Andre SchwarzORCID

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1 paper

Recent·Most cited

Cathepsin-dependent amyloid formation drives mechanical rupture of lysosomal membranes

Delong Li, Wenxin Zhang, Michaela Medina, Jan F. M. Stuke, Andre Schwarz, Jonas Brill, Johann Brenner, Felix Kraus, Simon Ohlerich, Javier Lizarrondo, Jeremy Pflaum, Julia H Grass, Lena-Marie Soltow, Dietmar Hammerschmid, Natalie Weber, , Florian Wilfling

This study shows that LLOMe forms amyloid structures inside lysosomes that mechanically rupture the lysosomal membrane, revealing a structural mechanism for lysosomal damage.

bioRxiv · Jan 19, 2026 · PreprintCell Biology