Delong Li

This paper introduces a method combining rotational and translational single-particle tracking to analyze nanoscale dynamics, showing it reveals distinct biophysical features of cellular compartments.

The paper develops a human stem cell toolkit for studying lysosomal storage disorders by generating proteomic data from induced cortical and dopaminergic-like neurons.

This study reveals the molecular mechanisms of cap-snatching by influenza polymerase using cryo-EM structures of FluPol bound to Pol II and DSIF.

This study shows that LLOMe forms amyloid structures inside lysosomes that mechanically rupture the lysosomal membrane, revealing a structural mechanism for lysosomal damage.